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Poster Session C: Friday, August 15, 2:00 – 5:00 pm, de Brug & E‑Hall

Representational dynamics of concurrent visuospatial working memories in Schizophrenia

Ines Pont Sanchis¹, Wiebke Hofmann, Daniel Senkowski, Bernhard Spitzer¹; ¹Max-Planck Institute

Presenter: Ines Pont Sanchis

Schizophrenia (SCZ) is a neuropsychiatric disorder whose core symptomatology includes impairments in working memory (WM) and higher executive functions. A wide range of WM function alterations in SCZ have been described, such as increased distractibility, decreased capacity and precision, differential biases, and more. In this ongoing study, we use a novel visual dual-task paradigm to examine the potential crosstalk between concurrent WM representations in SCZ versus healthy controls. Preliminary behavioral results indicate a possible attraction between concurrent WM items as well as an effect on response variance. Using simultaneous EEG and eye-tracking and representational similarity analysis, we explore the possible neural mechanisms underlying these effects, as well as the dynamics of maintained orientation representations. Finally, we examine previously observed oscillatory WM phenomena in SCZ, such as aberrant frontal gamma oscillations, and their relation to task performance.

Topic Area: Memory, Spatial Cognition & Skill Learning

Extended Abstract: Full Text PDF