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Poster Session B: Wednesday, August 13, 1:00 – 4:00 pm, de Brug & E‑Hall

Connectivity Effects of cTBS to the DLPFC: Examining beta phase synchronisation between the left and right DLPFC

Veronica Forslund¹, Alexandra Woolgar¹, Elizabeth Michael¹; ¹University of Cambridge

Presenter: Veronica Forslund

Transcranial magnetic stimulation (TMS) can induce lasting change in neural activity at both the stimulation site and brain-wide circuits. However, the efficacy of repetitive protocols in inducing brain-wide neuromodulation can vary. This pilot study used EEG to explore connectivity effects in the form of phase synchronisation between the left and right DLPFC after administration of continuous theta burst stimulation (cTBS) at the left Dorsal Lateral Prefrontal Cortex (DLPFC). To do this we used single-pulse TMS to probe connectivity effects before and after cTBS or sham cTBS. Unlike other forms of repetitive TMS (rTMS) and intermittent theta burst stimulation (iTBS), we found no change in connectivity following cTBS, highlighting the variability of neural outcomes that can follow apparently similar intervention protocols. Keywords: Functional connectivity; DLPFC; Neurostimulation; TMS; TBS; EEG; Phase synchronization

Topic Area: Brain Networks & Neural Dynamics

Extended Abstract: Full Text PDF