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Poster Session A: Tuesday, August 12, 1:30 – 4:30 pm, de Brug & E‑Hall

Interpretation of Individual Differences in Cognitive Computational Neuroscience

Jessica Schaaf¹, Steven Miletic, Anna C. K. van Duijvenvoorde, Hilde M. Huizenga; ¹Radboud University Medical Center

Presenter: Jessica Schaaf

Computational neuroscience offers a valuable opportunity to understand the neural mechanisms underlying behavior. Suppose that you fit a computational model to behavioral data to generate an individual-specific prediction error regressor. You in turn use this regressor to model activity in a brain region of interest. What do individual differences in the resulting regression weights mean? Typically researchers interpret these individual differences as differences in neural coding. Yet, in five scenarios, we illustrate through simulations that such individual differences may stem from other factors. By acknowledging these alternative interpretations of individual differences, and by openly sharing reproducible code, we aim to advance the understanding and interpretation of individual differences in computational neuroscience.

Topic Area: Methods & Computational Tools

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