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Poster Session B: Wednesday, August 13, 1:00 – 4:00 pm, de Brug & E‑Hall

Exploring the Cognitive Space: A Framework for Cognitive Function Mapping

Ana Fernanda Ponce¹, Demian Wassermann¹, Bertrand Thirion¹; ¹INRIA

Presenter: Ana Fernanda Ponce

Obtaining an accurate topography of cognitive functions is a major endeavour in human brain imaging. Recent advancements have been driven by intensive within-subject scanning, known as deep phenotyping, to address inter-subject variability. However, work is still needed to quantify how specific cognitive functions contribute to brain activation. In this study, we integrate statistical summaries from the Individual Brain Charting project (IBC) with the Cognitive Atlas. Each fMRI contrast map was annotated with cognitive components derived from its associated concepts. We then applied dictionary learning to estimate the contribution, or weight, of each component to a given contrast map. The resulting weights were used as regressors in a General Linear Model (GLM) analysis that incorporated contrast maps from all IBC tasks. This approach provided a more sensitive cognitive mapping of brain functions at the individual level.

Topic Area: Visual Processing & Computational Vision

Extended Abstract: Full Text PDF